Multi-kinase inhibitor I( MDK74978 | MDK 74978. Multi-kinase inhibitor I )

Catalog No. M17593 CAS No. 778274-97-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Multi-kinase inhibitor I
Note

Research use only, not for human use.
Brief Description

Multi-kinase inhibitor I is a Multi-kinase inhibitor.
Description

MDK74978, also known as Multi-kinase inhibitor I, is a Multi-kinase inhibitor. MDK74978 has CAS#778274-97-8. The last 5 digit was used in its name.
In Vitro

Multi-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl.
In Vivo

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Synonyms

MDK74978 | MDK 74978. Multi-kinase inhibitor I
Pathway

Angiogenesis
Target

HIF/HIF Prolyl-hydroxylase
Recptor

Multi-kinase
Research Area

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Indication

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CAS Number

778274-97-8
Formula Weight

418.38
Molecular Formula

C20H17F3N4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (239.02 mM)
SMILES

O=C(NCCO)c1ccc(c2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2)cc1
Chemical Name

N-(2-Hydroxyethyl)-4-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide

1.Chang Hsu Y, et al. Oncotarget. 2016 Nov 15

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